Michigan vs. Florida State odds: 2021 NCAA Tournament picks, March Madness Sweet 16 predictions from top model The SportsLine Projection Model has simulated Florida State vs. Michigan 10,000 times The No. 1 seed Michigan Wolverines own the second-longest active Sweet 16 streak in the nation as they prepare to face the fourth-seeded Florida State Seminoles in the 2021 NCAA Tournament on Sunday in Indianapolis. The Wolverines (22-4) are the last team standing among a record nine Big Ten Conference schools selected to the NCAA Tournament field and trail only top overall seed Michigan with four straight trips to the Sweet 16. The Seminoles (18-6), the only No. 4 seed left in the upset-filled tournament, are making their third consecutive appearance in the Sweet 16. Tip-off is at 5 p.m. ET on CBS from Bankers Life Fieldhouse. The winner advances to an Elite Eight matchup against either Alabama or UCLA. William Hill Sportsbook lists the Wolverines as two-point favorites, while the over-under for total points scored is 143 in the latest Michigan vs. Florida State odds. Before making any Florida State vs. Michigan picks, check out the college basketball predictions and betting advice from the SportsLine Projection Model. The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns. Now, the model has set its sights on Michigan vs. FSU in the Sweet 16 of the NCAA Tournament 2021. You can head to SportsLine to see its picks. Here are several college basketball odds and trends for FSU vs. Michigan: Michigan vs. FSU spread: Michigan -2 Michigan vs. FSU over-under: 143 points Michigan vs. FSU money line: Michigan -140; Florida State +120 MICH: The Wolverines' 20 NCAA wins since 2013 are the most of any school FSU: The Seminoles receive an average of 30.6 points from their bench Why Michigan can cover Despite the absence of second-leading scorer Isaiah Livers (foot), the Wolverines have five players averaging in double figures in the NCAA Tournament. Freshman center Hunter Dickinson is shooting 10-of-14 in the tournament and posted his sixth double-double of the season with 12 points and 11 boards vs. LSU the last time out. Eli Brooks is coming off a 21-point game and is 8-for-15 from the 3-point line in the last two contests. Sophomore Franz Wagner continues to do it all for Michigan, averaging 12.0 points, 8.0 boards and 4.0 assists in the tournament. The Wolverines have converted at least 20 free throws in each of their two NCAA wins and the ability to get to the line could be crucial against an opponent that has struggled to stay out of foul trouble. Michigan also has played outstanding perimeter defense, holding North Texas and LSU to a combined 7-of-33 from 3-point range. Why Florida State can cover While the Seminoles lack a go-to option offensively, four players are averaging in double figures and nine players see double-digit minutes. Senior guard M.J. Walker, the lone holdover from the 2018 squad that lost to Michigan in the Elite Eight, has scored a total of only 11 points in the first two rounds after averaging a team-leading 13.1 points during the regular season. He shot 44.1 percent from 3-point range in the regular season. Florida State shot better than 52 percent overall in each of its last two wins but has struggled from behind the arc, connecting on only 6-of-26 attempts. The lone exception was senior guard Anthony Polite, who buried 4-of-7 from 3-point range and scored a career-best 22 points in the 71-53 second-round drubbing of Colorado. Polite averaged 9.6 points during the regular season but boosted that mark to 17.0 on 13-of-20 shooting in the NCAA Tournament. How to make Florida State vs. Michigan picks The model is leaning over on the total, projecting the teams to combine for 147 points. It also says one side of the spread hits over 50 percent of the time. You can only see the pick at SportsLine. So who wins FSU vs. Michigan? And which side of the spread hits over 50 percent of the time? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.